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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
21.82
Human Site:
S276
Identified Species:
34.29
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S276
K
K
R
N
S
G
L
S
K
E
Q
K
E
K
Y
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S471
K
K
R
N
S
G
L
S
K
E
Q
K
E
K
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
T237
H
R
Q
T
Y
G
N
T
R
E
P
L
L
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S278
K
K
R
N
S
G
L
S
K
E
Q
K
E
K
Y
Rat
Rattus norvegicus
Q810T5
612
70496
S277
K
K
R
N
S
G
L
S
K
E
Q
K
E
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S276
K
K
R
N
S
G
L
S
K
E
Q
K
E
K
Y
Frog
Xenopus laevis
NP_001079995
617
71123
K276
K
V
T
E
L
R
K
K
R
N
S
G
L
T
K
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
T250
E
H
R
Q
T
H
G
T
T
R
E
P
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
G223
T
G
D
G
L
I
S
G
A
A
N
D
D
G
D
Honey Bee
Apis mellifera
XP_392324
916
101344
N568
K
G
N
T
G
D
G
N
E
S
D
S
S
C
E
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
Q140
A
E
S
V
D
P
L
Q
A
I
S
T
M
T
S
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
F186
G
C
D
S
R
G
H
F
T
G
K
F
T
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
E127
S
V
E
C
A
V
D
E
K
V
E
D
K
V
T
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
D127
N
T
D
V
M
D
L
D
N
L
N
V
Q
G
I
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
A188
M
D
E
D
E
I
P
A
A
K
K
Q
R
Q
P
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
6.6
6.6
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
N.A.
46.6
N.A.
100
100
N.A.
N.A.
100
13.3
33.3
N.A.
6.6
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
7
20
7
0
0
0
0
0
% A
% Cys:
0
7
0
7
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
7
20
7
7
14
7
7
0
0
7
14
7
0
7
% D
% Glu:
7
7
14
7
7
0
0
7
7
40
14
0
34
7
14
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% F
% Gly:
7
14
0
7
7
47
14
7
0
7
0
7
0
14
0
% G
% His:
7
7
0
0
0
7
7
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
14
0
0
0
7
0
0
0
0
7
% I
% Lys:
47
34
0
0
0
0
7
7
40
7
14
34
7
40
7
% K
% Leu:
0
0
0
0
14
0
47
0
0
7
0
7
20
7
0
% L
% Met:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
7
34
0
0
7
7
7
7
14
0
0
0
7
% N
% Pro:
0
0
0
0
0
7
7
0
0
0
7
7
0
0
7
% P
% Gln:
0
0
7
7
0
0
0
7
0
0
34
7
7
7
0
% Q
% Arg:
0
7
40
0
7
7
0
0
14
7
0
0
7
0
0
% R
% Ser:
7
0
7
7
34
0
7
34
0
7
14
7
7
0
7
% S
% Thr:
7
7
7
14
7
0
0
14
14
0
0
7
7
14
7
% T
% Val:
0
14
0
14
0
7
0
0
0
7
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _